pentobarbital will lower the level or impact of temsirolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital will lower the level or impact of alosetron by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Importance Unknown.Minimal (1)pentobarbital will minimize the level or outcome of paclitaxel protei